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Model‐Based Discovery and Development of Biopharmaceuticals: A Case Study of Mavrilimumab
Drug development is a lengthy, costly process with low probability of success. Biopharmaceuticals are highly specific molecules, with efficacy and safety closely tied to target biology and pharmacology. The “learning−predicting−confirming” continuum by translational and clinical modeling and simulat...
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| 出版年: | CPT Pharmacometrics Syst Pharmacol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5784736/ https://ncbi.nlm.nih.gov/pubmed/28836356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12245 |
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