Efficacy of T-DM1 for leptomeningeal and brain metastases in a HER2 positive metastatic breast cancer patient: new directions for systemic therapy - a case report and literature review

BACKGROUND: Herein, we report a complete response after whole brain radiotherapy (WBRT) and concomitant T-DM1 in a patient with HER2-positive metastatic breast cancer (MBC) and extensive brain and leptomeningeal involvement. CASE PRESENTATION: A 46 years old Caucasian woman with HER2-positive MBC an...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Ricciardi, Giuseppina Rosaria Rita, Russo, Alessandro, Franchina, Tindara, Schifano, Silvia, Mastroeni, Giampiero, Santacaterina, Anna, Adamo, Vincenzo
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
Subjects:
Case Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784540/
https://ncbi.nlm.nih.gov/pubmed/29370839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-3994-5
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