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Investigational therapies targeting the granulocyte macrophage colony-stimulating factor receptor-α in rheumatoid arthritis: focus on mavrilimumab

Mavrilimumab (formerly CAM-3001) is a high-affinity, immunoglobulin G4 monoclonal antibody (mAb) against the granulocyte macrophage colony-stimulating factor (GM-CSF) receptor-α chain. Phase I and II trials in patients with rheumatoid arthritis (RA) treated with mavrilimumab have shown encouraging r...

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Detalhes bibliográficos
Publicado no:Ther Adv Musculoskelet Dis
Principais autores: Cook, Andrew D., Hamilton, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784476/
https://ncbi.nlm.nih.gov/pubmed/29387176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759720X17752036
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