Evaluation of Preexisting Anti-Hemagglutinin Stalk Antibody as a Correlate of Protection in a Healthy Volunteer Challenge with Influenza A/H1N1pdm Virus

Influenza virus hemagglutinin (HA) surface glycoprotein is currently the primary target of licensed influenza vaccines. Recently, broadly reactive antibodies that target the stalk region of the HA have become a major focus of current novel vaccine development. These antibodies have been observed in...

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Veröffentlicht in:mBio
Hauptverfasser: Park, Jae-Keun, Han, Alison, Czajkowski, Lindsay, Reed, Susan, Athota, Rani, Bristol, Tyler, Rosas, Luz Angela, Cervantes-Medina, Adriana, Taubenberger, Jeffery K., Memoli, Matthew J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784259/
https://ncbi.nlm.nih.gov/pubmed/29362240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02284-17
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