Persistent activation of interlinked type 2 airway epithelial gene networks in sputum-derived cells from aeroallergen-sensitized symptomatic asthmatics

Atopic asthma is a persistent disease characterized by intermittent wheeze and progressive loss of lung function. The disease is thought to be driven primarily by chronic aeroallergen-induced type 2-associated inflammation. However, the vast majority of atopics do not develop asthma despite ongoing...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jones, Anya C., Troy, Niamh M., White, Elisha, Hollams, Elysia M., Gout, Alexander M., Ling, Kak-Ming, Kicic, Anthony, Stick, Stephen M., Sly, Peter D., Holt, Patrick G., Hall, Graham L., Bosco, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784090/
https://ncbi.nlm.nih.gov/pubmed/29367592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19837-6
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