An Open-Label Crossover Study of the Pharmacokinetics of the 60-mg Edoxaban Tablet Crushed and Administered Either by a Nasogastric Tube or in Apple Puree in Healthy Adults

BACKGROUND: Edoxaban is an orally active, direct factor Xa inhibitor indicated to reduce the risk of stroke and systemic embolism in non-valvular atrial fibrillation and for the treatment of venous thromboembolism. OBJECTIVES: This study assessed the pharmacokinetics, safety, and tolerability of the...

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Detaylı Bibliyografya
Yayımlandı:Clin Pharmacokinet
Asıl Yazarlar: Duchin, Kenneth, Duggal, Anil, Atiee, George J., Kidokoro, Motonori, Takatani, Tadanobu, Shipitofsky, Nicole Lazarus, He, Ling, Zhang, George, Kakkar, Tarundeep
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer International Publishing 2017
Konular:
Original Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784001/
https://ncbi.nlm.nih.gov/pubmed/28512699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-017-0554-0
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