A pilot study on clinical pharmacokinetics and preclinical pharmacodynamics of (+)-epicatechin on cardiometabolic endpoints

We reported that (−)-epicatechin can stimulate mitochondria biogenesis and improve metabolism. However, preliminary studies indicate that the (+) stereoisomer form may be more potent. We evaluated in a preliminary manner, the pharmacokinetics (PK) and initial safety analysis of (+)-epicatechin ((+)-...

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Detalhes bibliográficos
Publicado no:Food Funct
Main Authors: Moreno-Ulloa, Aldo, Nájera-García, Nayelli, Hernández, Marcela, Ramírez-Sánchez, Israel, Taub, Pam R., Su, Yongxuan, Beltrán-Partida, Ernesto, Ceballos, Guillermo, Dugar, Sundeep, Schreiner, George, Ciaraldi, Theodore P., Henry, Robert R., Villarreal, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783763/
https://ncbi.nlm.nih.gov/pubmed/29171848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7fo01028a
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