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A review of the pharmacology and clinical efficacy of brivaracetam

Brivaracetam (BRV; Briviact) is a new antiepileptic drug (AED) approved for adjunctive treatment of focal (partial-onset) seizures in adults. BRV is a selective, high-affinity ligand for synaptic vesicle 2A (SV2A) with 15- to 30-fold higher affinity than levetiracetam, the first AED acting on SV2A....

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Bibliografiske detaljer
Udgivet i:Clin Pharmacol
Main Authors: Klein, Pavel, Diaz, Anyzeila, Gasalla, Teresa, Whitesides, John
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783144/
https://ncbi.nlm.nih.gov/pubmed/29403319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S114072
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