Protocol for a multicentred randomised controlled trial investigating the use of personalised golimumab dosing tailored to inflammatory load in ulcerative colitis: the GOAL-ARC study (GLM dose Optimisation to Adequate Levels to Achieve Response in Colitis) led by the INITIAtive group (NCT 0268772)

INTRODUCTION: Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD), often leading to an impaired quality of life in affected patients. Current treatment modalities include antitumour necrosis factor (anti-TNF) monoclonal antibodies (mABs) including infliximab, adalimumab and golimum...

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Dades bibliogràfiques
Publicat a:BMJ Open Gastroenterol
Autors principals: Sheridan, Juliette, Coe, Carol Ann, Doran, Peter, Egan, Laurence, Cullen, Garret, Kevans, David, Leyden, Jan, Galligan, Marie, O’Toole, Aoibhlinn, McCarthy, Jane, Doherty, Glen
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2018
Matèries:
Inflammatory Bowel Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783109/
https://ncbi.nlm.nih.gov/pubmed/29379609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjgast-2017-000174
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