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P10.07 Sialate O-acetylesterase (SIAE) 
over-expression leads to a collapse of the mitochondrial membrane potential and predisposes cells to etoposide treatment in RES256 medulloblastoma cells

Medulloblastoma is the most common malignant paediatric brain tumour and is the leading cause of childhood cancer related mortality. Current treatment includes maximal safe surgical resection, radiotherapy if the patient is over 3 years of age, and high-dose chemotherapy that usually includes methot...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Mather, R. L., Loveson, K. F., Donovan, L. K., Pilkington, G. J., Fillmore, H. L.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5782724/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.231
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