P07.15 Diagnostic value of 2-hydroxyglutarate detection by 1H MR spectroscopy in patients with glioma and correlations with tumor phenotype and tissue dosage

INTRODUCTION: The overproduction of the oncometabolite 2-hydroxyglutarate (2HG) in IDH mutated gliomas can be detected non-invasively by magnetic resonance spectroscopy (MRS). In this study, we used two approaches for 2HG detection, e.g., difference spectroscopy (MEGA-PRESS) and conventional spectro...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Di Stefano, A. L., Branzoli, F., Ottolenghi, C., Capelle, L., Mokhtari, K., Villa, C. M., Giry, M., Marjanska, M., Lehericy, S., Sanson, M.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
P07 Neuroimaging of brain tumours
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5782622/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.126
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