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P01.07 Identification of novel molecular targets for TMZ-based therapies against glioblastoma: A comprehensive shRNA-based screen of DNA Damage Response factors
Despite surgical resection and genotoxic treatment with ionizing radiation and the DNA alkylating agent temozolomide (TMZ), glioblastoma (GBM) remains one of the most lethal cancers, due in great part to the action of DNA repair factors that drive resistance and lead to tumor relapse. Important feat...
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出版年: | Neuro Oncol |
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主要な著者: | , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Oxford University Press
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5782563/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.064 |
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