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P01.07 Identification of novel molecular targets for TMZ-based therapies against glioblastoma: A comprehensive shRNA-based screen of DNA Damage Response factors

Despite surgical resection and genotoxic treatment with ionizing radiation and the DNA alkylating agent temozolomide (TMZ), glioblastoma (GBM) remains one of the most lethal cancers, due in great part to the action of DNA repair factors that drive resistance and lead to tumor relapse. Important feat...

詳細記述

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書誌詳細
出版年:Neuro Oncol
主要な著者: Erasimus, H., Fritah, S., Haan, S., Herold-Mende, C., Klink, B., Masson, J. Y., Nazarov, P. V., Niclou, S. P., Van Dyck, E.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5782563/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.064
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