A Cell Culture Platform to Maintain Long-term Phenotype of Primary Human Hepatocytes and Endothelial Cells

BACKGROUND AND AIMS: Modeling interactions between primary human hepatocytes (PHHs) and primary human liver sinusoidal endothelial cells (LSECs) in vitro can help elucidate human-specific mechanisms underlying liver physiology/disease and drug responses; however, existing hepatocyte/endothelial cocu...

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Bibliografiske detaljer
Udgivet i:Cell Mol Gastroenterol Hepatol
Main Authors: Ware, Brenton R., Durham, Mitchell J., Monckton, Chase P., Khetani, Salman R.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5782488/
https://ncbi.nlm.nih.gov/pubmed/29379855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.11.007
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