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Premature polyadenylation of MAGI3 is associated with diminished N(6)-methyladenosine in its large internal exon
In cancer, tumor suppressor genes (TSGs) are frequently truncated, causing their encoded products to be non-functional or dominant-negative. We previously showed that premature polyadenylation (pPA) of MAGI3 truncates the gene, switching its functional role from a TSG to a dominant-negative oncogene...
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| I publikationen: | Sci Rep |
|---|---|
| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group UK
2018
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5780518/ https://ncbi.nlm.nih.gov/pubmed/29362392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19916-8 |
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