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The intronic G13964C variant in p53 is not a high-risk mutation in familial breast cancer in Australia

BACKGROUND: Mutations in BRCA1 and BRCA2 account for approximately 50% of breast cancer families with more than four affected cases, whereas exonic mutations in p53, PTEN, CHK2 and ATM may account for a very small proportion. It was recently reported that an intronic variant of p53 - G13964C - occur...

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Detalhes bibliográficos
Main Authors: Marsh, Anna, Spurdle, Amanda B, Turner, Bruce C, Fereday, Sian, Thorne, Heather, Pupo, Gulietta M, Mann, Graham J, Hopper, John L, Sambrook, Joseph F, Chenevix-Trench, Georgia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC57805/
https://ncbi.nlm.nih.gov/pubmed/11597326
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