Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population

Metabolomics-genome-wide association studies (mGWAS) have uncovered many metabolic quantitative trait loci (mQTLs) influencing human metabolic individuality, though predominantly in European cohorts. By combining whole-exome sequencing with a high-resolution metabolomics profiling for a highly consa...

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Publicat a:Nat Commun
Autors principals: Yousri, Noha A., Fakhro, Khalid A., Robay, Amal, Rodriguez-Flores, Juan L., Mohney, Robert P., Zeriri, Hassina, Odeh, Tala, Kader, Sara Abdul, Aldous, Eman K., Thareja, Gaurav, Kumar, Manish, Al-Shakaki, Alya, Chidiac, Omar M., Mohamoud, Yasmin A., Mezey, Jason G., Malek, Joel A., Crystal, Ronald G., Suhre, Karsten
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780481/
https://ncbi.nlm.nih.gov/pubmed/29362361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01972-9
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