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Hypoxia and hypoxia inducible factor-1α are required for normal endometrial repair during menstruation
Heavy menstrual bleeding (HMB) is common and debilitating, and often requires surgery due to hormonal side effects from medical therapies. Here we show that transient, physiological hypoxia occurs in the menstrual endometrium to stabilise hypoxia inducible factor 1 (HIF-1) and drive repair of the de...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5780386/ https://ncbi.nlm.nih.gov/pubmed/29362355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02375-6 |
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