Alzheimer’s Disease Mutant Mice Exhibit Reduced Brain Tissue Stiffness Compared to Wild-type Mice in both Normoxia and following Intermittent Hypoxia Mimicking Sleep Apnea

BACKGROUND: Evidence from patients and animal models suggests that obstructive sleep apnea (OSA) may increase the risk of Alzheimer’s disease (AD) and that AD is associated with reduced brain tissue stiffness. AIM: To investigate whether intermittent hypoxia (IH) alters brain cortex tissue stiffness...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Menal, Maria José, Jorba, Ignasi, Torres, Marta, Montserrat, Josep M., Gozal, David, Colell, Anna, Piñol-Ripoll, Gerard, Navajas, Daniel, Almendros, Isaac, Farré, Ramon
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780342/
https://ncbi.nlm.nih.gov/pubmed/29403429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00001
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