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GM-CSF promotes chronic disability in EAE by altering the composition of CNS myeloid cells, but is dispensable for disease induction
Granulocyte-macrophage colony-stimulating factor (GM-CSF) has been portrayed as a critical cytokine in the pathogenesis of experimental autoimmune encephalomyelitis (EAE) and, ostensibly, in multiple sclerosis. C57BL/6 mice deficient in GM-CSF are resistant to EAE induced by immunization with the 35...
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| 出版年: | J Immunol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5780231/ https://ncbi.nlm.nih.gov/pubmed/29288202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701484 |
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