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GM-CSF promotes chronic disability in EAE by altering the composition of CNS myeloid cells, but is dispensable for disease induction

Granulocyte-macrophage colony-stimulating factor (GM-CSF) has been portrayed as a critical cytokine in the pathogenesis of experimental autoimmune encephalomyelitis (EAE) and, ostensibly, in multiple sclerosis. C57BL/6 mice deficient in GM-CSF are resistant to EAE induced by immunization with the 35...

詳細記述

保存先:
書誌詳細
出版年:J Immunol
主要な著者: Duncker, Patrick C., Stoolman, Joshua S., Huber, Amanda K., Segal, Benjamin M.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780231/
https://ncbi.nlm.nih.gov/pubmed/29288202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701484
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