Allopregnanolone suppresses mechanical allodynia and internalization of neurokinin-1 receptors at the spinal dorsal horn in a rat postoperative pain model

BACKGROUND: To identify a new strategy for postoperative pain management, we investigated the analgesic effects of allopregnanolone (Allo) in an incisional pain model, and also assessed its effects on the activities of the primary afferent fibers at the dorsal horn. METHODS: In experiment 1, 45 rats...

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Detalhes bibliográficos
Publicado no:Korean J Pain
Main Authors: Fujita, Masahide, Fukuda, Taeko, Sato, Yasuhiro, Takasusuki, Toshifumi, Tanaka, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Pain Society 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780210/
https://ncbi.nlm.nih.gov/pubmed/29372021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3344/kjp.2018.31.1.10
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