Multimodal actions of the phytochemical sulforaphane suppress both AR and AR-V7 in 22Rv1 cells: Advocating a potent pharmaceutical combination against castration-resistant prostate cancer

Prostate cancer (PCa) cells expressing full-length androgen receptor (AR-FL) are susceptible to androgen deprivation therapy (ADT). However, outgrowth of castration-resistant prostate cancer (CRPC) can occur due to the expression of constitutively active (ligand-independent) AR splice variants, part...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: Khurana, Namrata, Kim, Hogyoung, Chandra, Partha K., Talwar, Sudha, Sharma, Pankaj, Abdel-Mageed, Asim B., Sikka, Suresh C., Mondal, Debasis
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780030/
https://ncbi.nlm.nih.gov/pubmed/28901514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.5932
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