Naringin protects myocardial cells from doxorubicin-induced apoptosis partially by inhibiting the p38MAPK pathway

Doxorubicin (DOX) has been widely used to treat cancers as a first-line antitumor drug. However, it causes severe, irreversible, dose-dependent cardiotoxicity. To evaluate the protective effects of naringin (NRG) on cardiotoxicity, the authors investigated the molecular mechanism of the p38MAPK sign...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Med Rep
Prif Awduron: Jian, Chun-Yan, Ouyang, Han-Bin, Xiang, Xian-Hong, Chen, Jia-Li, Li, Yong-Xin, Zhou, Xin, Wang, Jin-Yang, Yang, Yang, Zhong, En-Yi, Huang, Wen-Hua, Zhang, Hong-Wu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2017
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780003/
https://ncbi.nlm.nih.gov/pubmed/29152646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7823
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