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Directed transdifferentiation of Müller glial cells to photoreceptors using the sonic hedgehog signaling pathway agonist purmorphamine

Specification of distinct cell types from Müller glial cells is key to the potential application of endogenous repair in retinal regeneration. Sonic hedgehog (SHH) has been established as a potent mitogen for rat Müller glial cells, which also induces Müller glial cells to dedifferentiate and adopt...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Gu, Dandan, Wang, Songtao, Zhang, Shuai, Zhang, Peng, Zhou, Guomin
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5779882/
https://ncbi.nlm.nih.gov/pubmed/28983586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7652
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