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Metabolic engineering of Escherichia coli for the biosynthesis of 2-pyrrolidone
2-Pyrrolidone is a valuable bulk chemical with myriad applications as a solvent, polymer precursor and active pharmaceutical intermediate. A novel 2-pyrrolidone synthase, ORF27, from Streptomyces aizunensis was identified to catalyze the ring closing dehydration of γ-aminobutyrate. ORF27's tend...
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| Udgivet i: | Metab Eng Commun |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5779725/ https://ncbi.nlm.nih.gov/pubmed/29468109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meteno.2015.11.001 |
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