Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure

Adipose tissue lipolysis occurs during the development of heart failure as a consequence of chronic adrenergic stimulation. However, the impact of enhanced adipose triacylglycerol hydrolysis mediated by adipose triglyceride lipase (ATGL) on cardiac function is unclear. To investigate the role of adi...

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Gepubliceerd in:PLoS Genet
Hoofdauteurs: Salatzki, Janek, Foryst-Ludwig, Anna, Bentele, Kajetan, Blumrich, Annelie, Smeir, Elia, Ban, Zsofia, Brix, Sarah, Grune, Jana, Beyhoff, Niklas, Klopfleisch, Robert, Dunst, Sebastian, Surma, Michal A., Klose, Christian, Rothe, Michael, Heinzel, Frank R., Krannich, Alexander, Kershaw, Erin E., Beule, Dieter, Schulze, P. Christian, Marx, Nikolaus, Kintscher, Ulrich
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5779697/
https://ncbi.nlm.nih.gov/pubmed/29320510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007171
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