Mucosal immunization with PspA (Pneumococcal surface protein A)-adsorbed nanoparticles targeting the lungs for protection against pneumococcal infection

Burden of pneumonia caused by Streptococcus pneumoniae remains high despite the availability of conjugate vaccines. Mucosal immunization targeting the lungs is an attractive alternative for the induction of local immune responses to improve protection against pneumonia. Our group had previously desc...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Rodrigues, Tasson C., Oliveira, Maria Leonor S., Soares-Schanoski, Alessandra, Chavez-Rico, Stefanni L., Figueiredo, Douglas B., Gonçalves, Viviane M., Ferreira, Daniela M., Kunda, Nitesh K., Saleem, Imran Y., Miyaji, Eliane N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5779684/
https://ncbi.nlm.nih.gov/pubmed/29360883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191692
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