Mucosal immunization with PspA (Pneumococcal surface protein A)-adsorbed nanoparticles targeting the lungs for protection against pneumococcal infection

Burden of pneumonia caused by Streptococcus pneumoniae remains high despite the availability of conjugate vaccines. Mucosal immunization targeting the lungs is an attractive alternative for the induction of local immune responses to improve protection against pneumonia. Our group had previously desc...

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Veröffentlicht in:PLoS One
Hauptverfasser: Rodrigues, Tasson C., Oliveira, Maria Leonor S., Soares-Schanoski, Alessandra, Chavez-Rico, Stefanni L., Figueiredo, Douglas B., Gonçalves, Viviane M., Ferreira, Daniela M., Kunda, Nitesh K., Saleem, Imran Y., Miyaji, Eliane N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5779684/
https://ncbi.nlm.nih.gov/pubmed/29360883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191692
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