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VSL#3 Probiotic Stimulates T-Cell Protein Tyrosine Phosphatase-Mediated Recovery of IFN-γ Induced Intestinal Epithelial Barrier Defects

BACKGROUND: VSL#3 is a probiotic compound that has been used in the treatment of Inflammatory Bowel Disease (IBD). T-cell protein tyrosine phosphatase (TCPTP) is the protein product of the IBD candidate gene, PTPN2, and we have previously shown that it protects epithelial barrier function. The aim o...

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Detalhes bibliográficos
Publicado no:Inflamm Bowel Dis
Main Authors: Krishnan, Moorthy, Penrose, Harrison M., Shah, Nilay N., Marchelletta, Ronald R., McCole, Declan F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5779620/
https://ncbi.nlm.nih.gov/pubmed/27824650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000954
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