Long‐Term Exposure of Fine Particulate Matter Causes Hypertension by Impaired Renal D(1) Receptor–Mediated Sodium Excretion via Upregulation of G‐Protein–Coupled Receptor Kinase Type 4 Expression in Sprague‐Dawley Rats

BACKGROUND: Epidemiological evidence supports an important association between air pollution exposure and hypertension. However, the mechanisms are not clear. METHODS AND RESULTS: Our present study found that long‐term exposure to fine particulate matter (PM(2.5)) causes hypertension and impairs ren...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Lu, Xi, Ye, Zhengmeng, Zheng, Shuo, Ren, Hongmei, Zeng, Jing, Wang, Xinquan, Jose, Pedro A., Chen, Ken, Zeng, Chunyu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778966/
https://ncbi.nlm.nih.gov/pubmed/29307864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.007185
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