Simvastatin in combination with meclofenamic acid inhibits the proliferation and migration of human prostate cancer PC-3 cells via an AKR1C3 mechanism

Statins have become of interest in research due to their anticancer effects. However, the exact mechanism of their anticancer properties remains unclear. The authors previously reported that statins decrease intracellular cholesterol levels in androgen-independent prostate cancer cells. In de novo a...

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Veröffentlicht in:Oncol Lett
Hauptverfasser: Sekine, Yoshitaka, Nakayama, Hiroshi, Miyazawa, Yoshiyuki, Kato, Haruo, Furuya, Yosuke, Arai, Seiji, Koike, Hidekazu, Matsui, Hiroshi, Shibata, Yasuhiro, Ito, Kazuto, Suzuki, Kazuhiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778917/
https://ncbi.nlm.nih.gov/pubmed/29435052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7721
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