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Interference of P-REX2a may inhibit proliferation and reverse the resistance of SGC7901 cells to doxorubicin
Drug resistance inhibits the efficacy of doxorubicin in gastric cancer. Phosphatidylinositol 3,4,5-trisphosphate RAC exchanger 2a (P-REX2a) activates the phosphatidylinositol-3-kinase (PI3K)/protein kinase B (Akt) signaling pathway by binding to and inactivating phosphatase and tensin homolog (PTEN)...
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| Udgivet i: | Oncol Lett |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
D.A. Spandidos
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5778894/ https://ncbi.nlm.nih.gov/pubmed/29435055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7693 |
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