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Induction of apoptosis by an oleanolic acid derivative in SMMC-7721 human hepatocellular carcinoma cells is associated with mitochondrial dysfunction

The aim of the present study was to investigate the effects of an oleanolic acid derivative, a novel antitumor drug, on the growth of SMMC-7721 human hepatocellular carcinoma cells and the underlying mechanism. An MTT assay was performed to determine the cytotoxicity of the oleanolic acid derivative...

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Publicado en:Oncol Lett
Autores principales: Fan, Xinfeng, Wang, Penglong, Sun, Yaogui, Jiang, Junbing, Du, Haiyuan, Wang, Zhirui, Duan, Zhibian, Lei, Haimin, Li, Hongquan
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778847/
https://ncbi.nlm.nih.gov/pubmed/29467861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7653
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