Modelling the immunosuppressive effect of liver SBRT by simulating the dose to circulating lymphocytes: an in-silico planning study

BACKGROUND: Tumor immune-evasion and associated failure of immunotherapy can potentially be overcome by radiotherapy, which however also has detrimental effects on tumor-infiltrating and circulating lymphocytes (CL). We therefore established a model to simulate the radiation-dose delivered to CL. ME...

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Bibliografiske detaljer
Udgivet i:Radiat Oncol
Main Authors: Basler, L., Andratschke, N., Ehrbar, S., Guckenberger, M., Tanadini-Lang, S.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778751/
https://ncbi.nlm.nih.gov/pubmed/29357886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-018-0952-y
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