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MCM6 promotes metastasis of hepatocellular carcinoma via MEK/ERK pathway and serves as a novel serum biomarker for early recurrence

BACKGROUND: The high incidence of recurrence and metastasis of hepatocellular carcinoma (HCC) necessitate the discovery of new predictive biomarkers of invasion and prognosis. Minichromosome maintenance complex component 6 (MCM6), which has been reported to up-regulate in multiple malignancies, was...

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Bibliografski detalji
Izdano u:J Exp Clin Cancer Res
Glavni autori: Liu, Mingyu, Hu, Qiaoting, Tu, Mengxian, Wang, Xinyi, Yang, Zike, Yang, Guoxiong, Luo, Rongcheng
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778693/
https://ncbi.nlm.nih.gov/pubmed/29357919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0669-z
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