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MutScan: fast detection and visualization of target mutations by scanning FASTQ data

BACKGROUND: Some types of clinical genetic tests, such as cancer testing using circulating tumor DNA (ctDNA), require sensitive detection of known target mutations. However, conventional next-generation sequencing (NGS) data analysis pipelines typically involve different steps of filtering, which ma...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Chen, Shifu, Huang, Tanxiao, Wen, Tiexiang, Li, Hong, Xu, Mingyan, Gu, Jia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778627/
https://ncbi.nlm.nih.gov/pubmed/29357822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2024-6
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