Computational Pipeline for the PGV-001 Neoantigen Vaccine Trial

This paper describes the sequencing protocol and computational pipeline for the PGV-001 personalized vaccine trial. PGV-001 is a therapeutic peptide vaccine targeting neoantigens identified from patient tumor samples. Peptides are selected by a computational pipeline that identifies mutations from t...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Rubinsteyn, Alex, Kodysh, Julia, Hodes, Isaac, Mondet, Sebastien, Aksoy, Bulent Arman, Finnigan, John P., Bhardwaj, Nina, Hammerbacher, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778604/
https://ncbi.nlm.nih.gov/pubmed/29403468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01807
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