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Misfolding and aggregation of nascent proteins: a novel mode of toxic cadmium action in vivo

Cadmium is a highly poisonous metal and a human carcinogen, but the molecular mechanisms underlying its cellular toxicity are not fully understood. Recent findings in yeast cells indicate that cadmium exerts its deleterious effects by inducing widespread misfolding and aggregation of nascent protein...

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Detalhes bibliográficos
Publicado no:Curr Genet
Main Authors: Tamás, Markus J., Fauvet, Bruno, Christen, Philipp, Goloubinoff, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778182/
https://ncbi.nlm.nih.gov/pubmed/28936749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-017-0748-x
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