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CD4(+) T Helper Cells Play a Key Role in Maintaining Diabetogenic CD8(+) T Cell Function in the Pancreas
Autoreactive CD8(+) and CD4(+) T cells have been assigned independent key roles in the destruction of insulin-producing beta cells resulting in type 1 diabetes. Although CD4 help for the generation of efficient CD8(+) T cell responses in lymphoid tissue has been extensively described, whether these...
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| Veröffentlicht in: | Front Immunol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5778106/ https://ncbi.nlm.nih.gov/pubmed/29403481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.02001 |
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