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Over-expression of PPAR-γ2 gene enhances the adipogenic differentiation of hemangioma-derived mesenchymal stem cells in vitro and in vivo

BACKGROUND: Most of infantile hemangiomas involute into fibrofatty tissue in childhood, which indicates adipogenesis during this period. Mesenchymal stem cells (MSCs) contribute to the adipogenesis in IH. In this study, we investigated the effects of overexpression of PPAR-γ2 gene on the adipogenic...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Yuan, Si-Ming, Guo, Yao, Wang, Qian, Xu, Yuan, Wang, Min, Chen, Hai-Ni, Shen, Wei-Min
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777815/
https://ncbi.nlm.nih.gov/pubmed/29383203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23705
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