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Anti-tumor efficacy of oncolytic reovirus against gastrointestinal stromal tumor cells

Imatinib, a multitargeted receptor tyrosine kinase inhibitor, is used as the standard initial therapy against inoperable gastrointestinal stromal tumor (GIST). However, GIST can acquire resistance to imatinib within several years of therapy. The development of oncolytic reovirus as an anticancer age...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Inagaki, Yusuke, Kubota, Eiji, Mori, Yoshinori, Aoyama, Mineyoshi, Kataoka, Hiromi, Johnston, Randal N., Joh, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777799/
https://ncbi.nlm.nih.gov/pubmed/29383187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23361
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