GPER-independent inhibition of adrenocortical cancer growth by G-1 involves ROS/Egr-1/BAX pathway

We previously demonstrated that treatment of the H295R adrenocortical cancer cell line with the non-steroidal, high-affinity GPER (G protein-coupled estrogen receptor 1) agonist G-1 reduced tumor growth in vitro and in vivo through a GPER independent action. Moreover, we observed that G-1 treatment...

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Publicado en:Oncotarget
Autores principales: Casaburi, Ivan, Avena, Paola, De Luca, Arianna, Sirianni, Rosa, Rago, Vittoria, Chimento, Adele, Trotta, Francesca, Campana, Carmela, Rainey, William E., Pezzi, Vincenzo
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777797/
https://ncbi.nlm.nih.gov/pubmed/29383185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23314
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