Antidepressants, sertraline and paroxetine, increase calcium influx and induce mitochondrial damage-mediated apoptosis of astrocytes

The impacts of antidepressants on the pathogenesis of dementia remain unclear despite depression and dementia are closely related. Antidepressants have been reported may impair serotonin-regulated adaptive processes, increase neurological side-effects and cytotoxicity. An ‘astroglio-centric’ perspec...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Then, Chee-Kin, Liu, Kao-Hui, Liao, Ming-Hsuan, Chung, Kuo-Hsuan, Wang, Jia-Yi, Shen, Shing-Chuan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2017
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777788/
https://ncbi.nlm.nih.gov/pubmed/29383176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23302
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