Upregulation of RSPO2-GPR48/LGR4 signaling in papillary thyroid carcinoma contributes to tumor progression

The signaling pathway involving the R-spondins and its cognate receptor, GPR48/LGR4, is crucial in development and carcinogenesis. However, the functional implications of the R-spondin-GPR48/LGR4 pathway in thyroid remain to be identified. The aim of this study was to investigate the role of R-spond...

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Vydáno v:Oncotarget
Hlavní autoři: Kang, Yea Eun, Kim, Jin-Man, Kim, Koon Soon, Chang, Joon Young, Jung, Mingyu, Lee, Junguee, Yi, Shinae, Kim, Hyeon Woo, Kim, Jung Tae, Lee, Kyungmin, Choi, Min Jeong, Kang, Seul Ki, Lee, Seong Eun, Yi, Hyon-Seung, Koo, Bon Seok, Shong, Minho
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777747/
https://ncbi.nlm.nih.gov/pubmed/29383135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22692
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