Sodium fluoride induces apoptosis in mouse splenocytes by activating ROS-dependent NF-κB signaling

In this study, we investigated the roles of reactive oxygen species (ROS) and nuclear factor-κB (NF-κB) signaling in sodium fluoride-induced DNA damage and apoptosis in mouse splenocytes. Intragastric administration of 12, 24 or 48 mg/kg sodium fluoride resulted in a time- and dose-dependent increas...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Deng, Huidan, Kuang, Ping, Cui, Hengmin, Luo, Qin, Liu, Huan, Lu, Yujiao, Fang, Jing, Zuo, Zhicai, Deng, Junliang, Li, Yinglun, Wang, Xun, Zhao, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper: Gerotarget (Focus on Aging)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777703/
https://ncbi.nlm.nih.gov/pubmed/29383091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22826
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