Parallel PI3K, AKT and mTOR inhibition is required to control feedback loops that limit tumor therapy

Targeting the PI3K pathway has achieved limited success in cancer therapy. One reason for the disappointing activity of drugs that interfere with molecules that are important player in this pathway is the induction of multiple feedback loops that have been only partially understood. To understand th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sathe, Anuja, Chalaud, Géraldine, Oppolzer, Immanuel, Wong, Kit Yeng, von Busch, Margarita, Schmid, Sebastian C., Tong, Zhichao, Retz, Margitta, Gschwend, Juergen E., Schulz, Wolfgang A., Nawroth, Roman
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777650/
https://ncbi.nlm.nih.gov/pubmed/29357370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190854
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados