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The Expanding Landscape of Alternative Splicing Variation in Human Populations

Alternative splicing is a tightly regulated biological process by which the number of gene products for any given gene can be greatly expanded. Genomic variants in splicing regulatory sequences can disrupt splicing and cause disease. Recent developments in sequencing technologies and computational b...

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Bibliographic Details
Published in:Am J Hum Genet
Main Authors: Park, Eddie, Pan, Zhicheng, Zhang, Zijun, Lin, Lan, Xing, Yi
Format: Artigo
Language:Inglês
Published: Elsevier 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777382/
https://ncbi.nlm.nih.gov/pubmed/29304370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2017.11.002
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