Elevated sodium chloride drives type I interferon signaling in macrophages and increases antiviral resistance

Type I IFN production and signaling in macrophages play critical roles in innate immune responses. High salt (i.e. high concentrations of NaCl) has been proposed to be an important environmental factor that influences immune responses in multiple ways. However, it remains unknown whether high salt r...

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Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Zhang, Wu-Chang, Du, Lin-Juan, Zheng, Xiao-Jun, Chen, Xiao-Qing, Shi, Chaoji, Chen, Bo-Yan, Sun, Xue-Nan, Li, Chao, Zhang, Yu-Yao, Liu, Yan, Xiao, Hui, Leng, Qibin, Jiang, Xinquan, Zhang, Zhiyuan, Sun, Shuyang, Duan, Sheng-Zhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777245/
https://ncbi.nlm.nih.gov/pubmed/29203528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.805093
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