Labile plasma iron levels predict survival in patients with lower-risk myelodysplastic syndromes

Red blood cell transfusions remain one of the cornerstones in supportive care of lower-risk patients with myelodysplastic syndromes. We hypothesized that patients develop oxidant-mediated tissue injury through the formation of toxic iron species, caused either by red blood cell transfusions or by in...

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Published in:Haematologica
Main Authors: de Swart, Louise, Reiniers, Chloé, Bagguley, Timothy, van Marrewijk, Corine, Bowen, David, Hellström-Lindberg, Eva, Tatic, Aurelia, Symeonidis, Argiris, Huls, Gerwin, Cermak, Jaroslav, van de Loosdrecht, Arjan A., Garelius, Hege, Culligan, Dominic, Macheta, Mac, Spanoudakis, Michail, Panagiotidis, Panagiotis, Krejci, Marta, Blijlevens, Nicole, Langemeijer, Saskia, Droste, Jackie, Swinkels, Dorine W., Smith, Alex, de Witte, Theo
Format: Artigo
Language:Inglês
Published: Ferrata Storti Foundation 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777192/
https://ncbi.nlm.nih.gov/pubmed/29122992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.171884
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