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Field- and clinically derived estimates of Wolbachia-mediated blocking of dengue virus transmission potential in Aedes aegypti mosquitoes

The wMel strain of Wolbachia can reduce the permissiveness of Aedes aegypti mosquitoes to disseminated arboviral infections. Here, we report that wMel-infected Ae. aegypti (Ho Chi Minh City background), when directly blood-fed on 141 viremic dengue patients, have lower dengue virus (DENV) transmissi...

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Publicado en:Proc Natl Acad Sci U S A
Main Authors: Carrington, Lauren B., Tran, Bich Chau Nguyen, Le, Nhat Thanh Hoang, Luong, Tai Thi Hue, Nguyen, Truong Thanh, Nguyen, Phong Thanh, Nguyen, Chau Van Vinh, Nguyen, Huong Thi Cam, Vu, Trung Tuan, Vo, Long Thi, Le, Dui Thi, Vu, Nhu Tuyet, Nguyen, Giang Thi, Luu, Hung Quoc, Dang, Anh Duc, Hurst, Timothy P., O’Neill, Scott L., Tran, Vi Thuy, Kien, Duong Thi Hue, Nguyen, Nguyet Minh, Wolbers, Marcel, Wills, Bridget, Simmons, Cameron P.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777059/
https://ncbi.nlm.nih.gov/pubmed/29279375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715788115
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