Mixed signature of activation and dysfunction allows human decidual CD8(+) T cells to provide both tolerance and immunity

Understanding how decidual CD8(+) T cell (CD8(+) dT) cytotoxicity is regulated and how these cells integrate the competing needs for maternal–fetal tolerance and immunity to infection is an important research and clinical goal. Gene-expression analysis of effector-memory CD8(+) dT demonstrated a mix...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: van der Zwan, Anita, Bi, Kevin, Norwitz, Errol R., Crespo, Ângela C., Claas, Frans H. J., Strominger, Jack L., Tilburgs, Tamara
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777048/
https://ncbi.nlm.nih.gov/pubmed/29259116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1713957115
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